New-Tech Europe | Sep 2017 | Digital Edition
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recover from stroke. “This is difficult to imagine, but it is achievable, successfully working about 98 percent of the time. With this technology, we can convert skin cells into elements of any organ with just one touch. This process only takes less than a second and is non-invasive, and then you’re off. The chip does not stay with you, and the reprogramming of the cell starts. Our technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary,” said Sen, who also is executive director of Ohio State’s Comprehensive Wound Center. TNT technology has two major components: First is a nanotechnology-based chip designed to deliver cargo to adult cells in the live body. Second is the design of specific biological cargo for cell conversion. This cargo, when delivered using the chip, converts an adult cell from one type to another, said first author Daniel Gallego-Perez, an assistant professor of
biomedical engineering and general surgery who also was a postdoctoral researcher in both Sen’s and Lee’s laboratories. TNT doesn’t require any laboratory-based procedures and may be implemented at the point of care. The procedure is also non-invasive. The cargo is delivered by zapping the device with a small electrical charge that’s barely felt by the patient. “The concept is very simple,” Lee said. “As a matter of fact, we were even surprised how it worked so well. In my lab, we have ongoing research trying to understand the mechanism and do even better. So, this is the beginning, more to come.” Researchers plan to start clinical trials next year to test this technology in humans, Sen said. Funding for this research was provided by Ohio State’s Center for Regenerative Medicine and Cell-Based Therapies, Ohio State’s Nanoscale Science and Engineering Center and Leslie and Abigail Wexner.
SCHURTER is IATF 16469 Certified
The interdisciplinary and process- oriented aspects are gaining in importance. The goal is clearly defined: The reliability of the processes is being increased, allowing product quality to be maintained at a high and – very important – constant level. The aim is zero errors. A goal that requires a continuous
SCHURTER AG in Lucerne successfully passed the certification audits according to the new IATF 16949:2016 automotive standard. This new standard of the IATF (International Automotive Task Force) demands the highest system and process quality standards of a company. Certifications are the mark of distinction for a company. They
optimization process. Thus, this certification is not important just for automotive customers. It is important for all SCHURTER customers. About IATF 16469 In October 2016, the new IATF 16949:2016 standard was published. The first edition of IATF 16949 replaces ISO/TS 16949:2009. The aim of the revised IATF 16949 standard is continuous improvement of the system and process quality of companies in the automotive industry. The continuous optimization process is intended to increase customer satisfaction, detect errors and risks in the production process and the supply chain, eliminate their causes and check the corrective actions and preventive measures taken for their effectiveness.
recognize a defined quality level. The IATF 16949:2016 automotive standard represents one of the strictest and most demanding certifications. SCHURTER approached this certification with the clear objective of further development of its own company. SCHURTER wishes to engage in continuous improvement in order to meet the steadily growing requirements of its customers now and in the future. After scrupulous analyses, internal workflows were optimized. The documentation for all products andproduction processes was refined down to the most minute detail. Even management was included and held accountable. In the future, there will be a greater integration into all process and production phases.
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